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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A5 All Species: 27.27
Human Site: T448 Identified Species: 46.15
UniProt: Q9NRA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA2 NP_036566.1 495 54640 T448 P V I A K S L T P D N T V G E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112868 495 54586 T448 P V I A K S L T P D N T V G E
Dog Lupus familis XP_532204 495 54438 T448 P V I A K S L T P D N T I R E
Cat Felis silvestris
Mouse Mus musculus Q8BN82 495 54351 T448 P I I A K S L T P D N T I R E
Rat Rattus norvegicus Q7TSF2 588 64736 T472 P L I V G A M T K H K T R E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506458 459 50560 G425 L V A A G F I G C D Y S L A V
Chicken Gallus gallus NP_001026257 484 53539 T437 P V I A K N L T H N N T V G E
Frog Xenopus laevis Q6INC8 576 63887 T460 P L I V G A M T K H K T R E E
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 T473 P L I V G A L T K H K T R L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 I453 P I A A G H L I S D P S K P M
Honey Bee Apis mellifera XP_395682 508 56831 V446 P I I T G Y I V Q N K S P E E
Nematode Worm Caenorhab. elegans Q03567 493 52719 T431 P A V S S Y L T P N G T Q E E
Sea Urchin Strong. purpuratus XP_780445 542 58846 V456 P S M V G L Y V T N Q Y D I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 L507 T A A T G Y I L Q R G S W D D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.7 89.2 N.A. 86.2 31.6 N.A. 61.4 77.7 31.9 32.5 N.A. 36.6 38.5 40.2 42.6
Protein Similarity: 100 N.A. 99.8 94.3 N.A. 92.7 48.6 N.A. 69.4 87.2 47.9 48.9 N.A. 52.5 57.4 59.3 62.1
P-Site Identity: 100 N.A. 100 86.6 N.A. 80 33.3 N.A. 20 80 33.3 40 N.A. 26.6 20 40 6.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 53.3 N.A. 40 93.3 53.3 53.3 N.A. 40 46.6 60 20
Percent
Protein Identity: N.A. N.A. N.A. 32.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 22 50 0 22 0 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 43 0 0 8 8 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 29 72 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 58 0 0 8 0 0 15 0 0 22 0 % G
% His: 0 0 0 0 0 8 0 0 8 22 0 0 0 0 0 % H
% Ile: 0 22 65 0 0 0 22 8 0 0 0 0 15 8 0 % I
% Lys: 0 0 0 0 36 0 0 0 22 0 29 0 8 0 0 % K
% Leu: 8 22 0 0 0 8 58 8 0 0 0 0 8 8 0 % L
% Met: 0 0 8 0 0 0 15 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 8 0 0 0 29 36 0 0 0 0 % N
% Pro: 86 0 0 0 0 0 0 0 36 0 8 0 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 15 0 8 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 22 15 0 % R
% Ser: 0 8 0 8 8 29 0 0 8 0 0 29 0 0 8 % S
% Thr: 8 0 0 15 0 0 0 65 8 0 0 65 0 0 0 % T
% Val: 0 36 8 29 0 0 0 15 0 0 0 0 22 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 22 8 0 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _